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Glenn
Penner (Chemistry) 
Vladimir
Ladizhansky (Protein NMR Research Group, Physics)
Jim
Davis (Physics)
Kenneth
R. Jeffrey (Physics)
Valerie
Robertson (NMR Facility)
Office,
Clerical and Technical
Position covered by the Collective Agreement with USW Local 4120
Nuclear Magnetic Resonance Technician
Dean's Office, College of Physical and Engineering Science
Hiring #:2011-0304
http://www.uoguelph.ca/hr/job-posting-2011-0304
For application instructions, please visit
http://www.uoguelph.ca/hr/careers-guelph/how-apply
The University of Guelph Nuclear Magnetic Resonance (NMR) Centre is equipped with seven Bruker NMR spectrometers, and provides analytical research services, and technical and scientific advice, to both academic and industrial communities. The NMR Technician will assist in the operation and maintenance of the Centre's equipment and associated computer network. Specific duties will include: running samples on both solid and solution state NMR spectrometers; solving complex problems with equipment; maintaining GLP system for industrial samples as required; receiving and handling customer complaints; coordinating instrumental access by users; training non specialized users, such as graduate students and faculty, providing individual training as necessary; monitoring authorized users and recommending retraining or additional training as necessary; maintaining super-conducting magnets; running periodic checks on the NMR spectrometers; performing preliminary diagnosis of electronic malfunctions and minor repairs and other associated duties.
Requirements of the position: a Master's Degree in Chemistry, Physics or Biochemistry combined with 2 years related NMR experience, or an equivalent combination of education and experience. Additional requirements include: a background in NMR spectroscopy; strong customer service skills; scheduling and running training sessions; computer skills; strong organizational abilities; experience with analysing data and excellent oral and written communication skills.
Position
Number: 256-003
Classification: USW, Local 4120 Band 7*
Salary Range:
$25.93 Minimum
$35.06 Job Rate (level 7)
$36.67 Maximum
*Tentative evaluation; subject to committee review.
Posting
Date: 2011 12 07
Closing Date: 2011 12 14
Stable
Isotopes for Structural Biomolecular NMR (July 22/11)
Cambridge Isotope Laboratories (CIL) made available a series of application notes on the use of stable isotopes in Biomolecular NMR. These application notes were written by some of the world's leading researches in the field, including several Canadian scientists.
Lewis Kay (University of Toronto) "Alanine Probes of Supra-Molecular Structure and Dynamics", page 9.
Leonid S. Brown and Vladimir Ladizhansky (University of Guelph) "Pichia pastoris as a Eukaryotic Protein Isotope-Labeling System", pages 14-15.
Ying Fan, Lichi Shi, Vladimir Ladizhansky and Leonid S. Brown (University of Guelph) "Uniform Isotope Labeling of Eukaryotic Proteins in Methylotrophic Yeast for High-Resolution NMR Studies - Extension to Membrane Proteins", Application Note 26, pages 71-74.
Recent research by Gang Wu's group (Queen's University) is cited as an example of advanced 17O NMR spectroscopy in large protein-ligand complexes in solution and in the solid state, "17O NMR reagents", page 34.
These
application notes are available for download as a PDF file (5.1MB) "Stable
Isotopes for Structural Biomolecular NMR Catalog" at:
http://www.isotope.com/cil/literature/research_literature/index.cfm
Renee Webber (University of Guelph) June 2011
Supervisors:
Prof. Glenn Penner
Ph.D. thesis: "An NMR Spectroscopic and Quantum Chemical Investigation
of Hydrogen Bonding In Solids"
External Examiner: Prof. Gang Wu (Queen's University)
 |
The Spring 2011 Issue of the "Canadian NMR Research" news bulletin featuring the Guest Editorial by James Davis and Vladimir Ladizhansky (University of Guelph) and other Canadian NMR news is now available for download. You are welcome to share this bulletin with your colleagues and students. |
Bruker has announced that the first commercial 395 GHz solid-state DNP-NMR spectrometer (600 MHz) will be installed at the University of Guelph (read the full press-release).
L.
Shi, I. Kawamura, K.-H. Jung, L.S. Brown, and V. Ladizhansky, "Conformation
of a Seven-Helical Transmembrane Photosensor in the Lipid Environment,"
Angewandte Chemie International Edition (2011) online. http://dx.doi.org/10.1002/anie.201004422
 |
Solid-State
NMR Studies of Biopolymers
edited by Anne McDermott, Tatyana Polenova Hardcover: 592 pages Publisher: Wiley; September 2010 Language: English ISBN: 978-0470721223 http://www.amazon.com/dp/0470721227 http://www.amazon.ca/dp/0470721227 |
Wiley: "The field of solid state NMR of biological samples has blossomed recently, requiring new practitioners in industry and academia to have fundamental understanding of this technology. Discussed are Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers as well as RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. Including practical examples of biochemical applications, this dependable EMR handbook thoroughly examines a field sure to expand in the years ahead."
Canadian contributions
V. Ladizhansky, "Dipolar-Based Torsion Angle Measurements for Protein Structure Determination," Chapter 14, Solid-State NMR Studies of Biopolymers (EMR Books), Eds. A.E. McDermott and T. Polenova, Wiley (2010) pp. 273-284. http://dx.doi.org/10.1002/9780470034590.emrstm1153
M. Auger, "Structural and Dynamics Studies of Lipids by Solid-State NMR ", Chapter 27, Solid-State NMR Studies of Biopolymers (EMR Books), Eds. A.E. McDermott and T. Polenova, Wiley (2010) pp. 463-472. http://dx.doi.org/10.1002/9780470034590.emrstm1100
Table of Contents and Google preview are available (Wiley).
Government of Canada has announced today (external link) an investment of $165.5 million to fund 187 new or renewed Canada Research Chairs in 44 Canadian universities. This includes renewal of two Chairs involved in magnetic resonance research.
Gary Shaw (University of Western Ontario) Canada Research Chair Tier 1 in Structural Neurobiology
Vladimir Ladizhansky (University of Guelph) Canada Research Chair Tier 2 in Biophysics
Our sincere congratulations to Gary and Vladimir with this well-deserved recognition.
Lichi Shi (University of Guelph) December 2009
Supervisors:
Leonid Brown and Vladimir Ladizhansky
Ph.D. thesis: “Solid-state NMR study of proteorhodopsin in the lipid environment: spectra assignments and structural insights”
Mumdooh Ahmed (University of Guelph) August 2009
Supervisors:
George Harauz and Vladimir Ladizhansky
Ph.D. thesis: “Dynamics and Induced Structure of intrinsically disordered
myelin proteins by NMR spectroscopy”
Rafal Janik (Protein NMR Research Group, University of Guelph) October 2008
Research
supervisor: Vladimir Ladizhansky
M.Sc. thesis: “Development of long-range chemical shift correlation experiments using homonuclear rotary resonance”
April 29, 2008
Read
a feature article about Valerie Robertson, an NMR Facility Manager at the
University of Guelph, in the April 2008 issue of At Guelph, the University
of Guelph's official campus newspaper (external
link ).
Photo from: www.uoguelph.ca