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Manager - Structural Biology Facility (Department of Biochemistry and Molecular Medicine, Université de Montréal) <NEW

Massey University, Palmerston North, New Zealand (Chemistry/Biophysics Postgraduate Scholarship) <NEW

University of Louisville (NMR Postdoc in protein dynamics)

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CanadianManager - Structural Biology Facility, Department of Biochemistry and Molecular Medicine, Université de Montréal (April 25/17)

General description

As a structural biology specialist (NMR spectroscopy and X-ray crystallography), you will be responsible for optimal usage of a new structural biology facility at UdeM under the direction of the professor responsible for the facility and in close collaboration with members of the department. Your duties will include user training, equipment operation and maintenance as well as development of experimental protocols associated with research projects and academic training.

Main duties
• Provide user training and oversee instrument usage of all the equipment within the structural biology facility (500 MHz, 600 MHz, and 700 MHz NMR spectrometers, liquid handling robots, stereomicroscopes, crystallisation chambers, light-scattering equipment (MALS/RI), etc)
• Assure the optimal operation of equipment and offer technical assistance when needed
• Assure the maintenance of the structural biology equipment
• Develop and implement protocols for instrument maintenance, data collection and analysis, both in French and English
• Contribute to budget planning for the facility and to purchasing consumables and new equipment
• Collaborate with departmental staff for planning of instrument schedule, billing, and maintenance of a web page describing the facility
• Participate in the development of didactic material for teaching undergraduate and graduate students
• Serve as a resource for users, providing expert advice in experiment planning and data analysis
• Coordinate with manufacturers for preventive maintenance and repairs
• Maintain professional and technical knowledge
• Promote the facility
• Ensure the safety of users and personnel who have access to the facility

Skills and qualifications

Required education and experience:
• Applicants must have a MSc and three (3) years of relevant experience or PhD degree in Chemistry, Biochemistry or related discipline

Preferred qualifications:
• Experience in structural biology, especially in NMR spectroscopy and X-ray crystallography
• Experience in using computer software and developing computer scripts for structural biology applications
• Oral and written communication skills, both in French and English
• Experience in instrument maintenance and repair
• Demonstrated ability to train students
• Other qualifications: autonomy, scientific rigor, sense of organization, capacity for teamwork

More information
• Salary scale (hourly) : $27.36 to $39.31
• Supervisor: Pascale Legault, Professor, Department of Biochemistry and Molecular Medicine
• Location : Roger-Gaudry Building, Université de Montréal, Montreal, Quebec, Canada
• Working hours: Monday to Friday, 9h00 to 17h00

Please send a curriculum vitae listing all publications and a list of three references as well as a cover letter to: [ pascale.legault "at" umontreal.ca ]

Pascale Legault, Ph.D.
Département de Biochimie et Médecine Moléculaire
Université de Montréal
Tel: 514-343-7326
E-mail: pascale.legault "at" umontreal.ca
URL: http://airen.bcm.umontreal.ca

Chemistry/Biophysics Postgraduate Scholarship, Massey University, Palmerston North, New Zealand (April 20/17)

The Institute of Fundamental Sciences, Massey University offers a PhD-scholarship for an enthusiastic and motivated individual who is interested in chemistry, biochemistry, chemical biology. The project is a part of a current research programme devoted to the family of enzymes, called APOBEC3, that mutate DNA and RNA and in this way promote mutagenesis in several cancers resulting in drug resistance, rapid disease development and poor survival prognosis. This PhD study will be focused on understanding of how APOBEC3 proteins interact with recently discovered RNA substrates. Our programme is a part of collaboration between Dr Elena Harjes (e.harjes "at" massey.ac.nz, NMR analysis of RNA-protein interactions), Assoc. Prof. Vyacheslav V. Filichev (v.filichev "at" massey.ac.nz, DNA/RNA chemistry) and Prof. Geoffrey B. Jameson (g.b.jameson "at" massey.ac.nz, structural biology and protein biochemistry). It also involves connections with Reuben Harris's Cancer program, University of Minnesota, USA.


The Chemistry and Biophysics group is part of the Institute of Fundamental Sciences (IFS) which gathers scientists from varied fields working on cutting edge problems within and across their disciplines.

There is a large, diverse and active community of PhD students and postdoctoral researchers at Massey. A good range of modern instruments and facilities available for research and teaching, excellent library, computing (locally or at the nationwide scale, e.g. NeSi, https://www.nesi.org.nz/ ), sustained programmes of research seminars are available to the successful candidate.

Candidate and conditions:
The anticipated admission standard for this PhD position is a 1st class or high upper 2nd class Honours degree, or a Master's degree with merit or distinction, in Chemistry/Biochemistry or a related quantitative discipline. Overseas qualifications of an equivalent standard are also acceptable. Experience in synthetic chemistry is essential and experience with the synthesis (chemical or biochemical) and purification of nucleic acids is highly desirable. The interest in biological questions, experience with protein purification, some familiarity with NMR spectroscopy would be considered favourable.

The PhD studentship will be three years in duration and covers tuition fees plus a stipend of NZ$ 25,000 per annum (non-taxable). In addition, some reasonable funds are available to students e.g. for travel to international conferences, or small equipment. There would be the possibility to gain some experience in teaching if desired. The location of the PhD is at the Manawatu Campus of Massey University, in Palmerston North, a small, very affordable yet lively, enjoyable and culturally diverse city in the North Island of New Zealand.

The deadline for the application is 11/05/2017. Applications will be considered on a rolling basis until the studentship is filled. Apply as soon as possible to avoid disappointment! The ideal enrolment date is September 2017. For further information and informal discussions of potential projects please contact [ e.harjes "at" massey.ac.nz ]

Postdoctoral position at University of Louisville (Jan 18/17)

The Li lab in the Department of Chemistry at University of Louisville is seeking a highly motivated postdoctoral researcher to join our lab immediately.

Our research interests focus on applying solution NMR techniques to understand the functional roles of protein conformational dynamics in the deubiquitinase family. We’re especially interested in deubiquitinases that are involved in signaling pathways implicated in cancer and autoimmune diseases. To accomplish our research goals, we complement solution NMR spectroscopy with other biophysical and biochemical techniques, such as enzymatic assays, fluorescence spectroscopy, isothermal titration calorimetry, and X-ray crystallography. We have regular access to several NMR spectrometers on campus, ranging from 500 MHz to 800 MHz. The 600 MHz and 700 MHz spectrometers are equipped with cryoprobes. Other instruments for biophysical characterization are available in the biophysics core facility located in the medical school.

Successful candidates should possess a Ph.D. in biochemistry or a related field at the start date. Prior experience in solution or solid-state NMR spectroscopy and preparation of protein NMR samples is required. Additional experiences in NMR method development, molecular dynamics simulation and X-ray crystallography are highly desirable. More information about our research can be found in the lab website http://www.linmrlab.com

Interested candidates should send a letter of interest, CV and contract information for three references to Dr. Ying Li
[ying.li.1 "at" louisville.edu]

Ying Li, Ph.D.
Assistant Professor
Department of Chemistry
University of Louisville
2320 S Brook Street
Louisville, KY 40208

Email: ying.li.1 "at" louisville.edu
Phone: 502-852-5975

Web: http://www.linmrlab.com

NMR jobs on other web-sites (external links)

NMR jobs listed by the International Society of Magnetic Resonance (ISMAR) https://www.weizmann.ac.il/ISMAR/career-center

NMR jobs on the NMR Information Server

List of NMR jobs and Post-Doc positions maintained by Dror Warschawski (look under "Archive" on the left panel)

Association of Managers in Magnetic Resonance Laboratories (AMMRL) Email Archives

Wiley Job Network: Search Healthcare, Science, and Academic Jobs http://www.wileyjobnetwork.com/

Various positions at Canadian Universities

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