McGill University
people & news	publications

2012

Z. Wu, Y. Sun, I.S. Butler, "Optimized structures and theoretical 1H NMR spectral analysis of the methylene protons in dibenzyl sulfoxide," Advanced Materials Research 391-392 (2012) 1368-1374. http://dx.doi.org/10.4028/www.scientific.net/AMR.391-392.1368

Z. Wu, I.S. Butler, "Structures, Theoretical Vibrational Frequency and 1H NMR Spectral Analysis of Pyrazine-Dibenzylsulfoxide Platinum(II) Complexes," Advanced Materials Research 391-392 (2012) 1375-1382. http://dx.doi.org/10.4028/www.scientific.net/AMR.391-392.1375

2011

T. Moldoveanu, Q. Liu, D.R. Green and K. Gehring, "BAK," Encyclopedia of Inorganic and Bioinorganic Chemistry, Wiley (2011).
http://dx.doi.org/10.1002/9781119951438.eibc0662

T. Miletti, P.J. Farber, A. Mittermaier, "Active site dynamics in NADH oxidase from Thermus thermophilus studied by NMR spin relaxation," Journal of Biomolecular NMR 51 (2011) 71-82.
http://dx.doi.org/ 10.1007/s10858-011-9542-0

R. Soudy, A. Gill, T. Sprules, A. Lavasanifar, and K. Kaur, "'Proteolytically Stable Cancer Targeting Peptides with High Affinity for Breast Cancer Cells," J. Med. Chem. 4 (2011) 7523-7534. http://dx.doi.org/10.1021/jm200750x

A.C.Y. Fan, G. Kozlov, A. Hoegl, R.C. Marcellus, M.J.H. Wong, K. Gehring and J.C. Young, "Interaction between the human mitochondrial import receptors Tom20 and Tom70 in vitro suggests a chaperone displacement mechanism," Journal of Biological Chemistry 286 (2011) 32208-32219. http://dx.doi.org/10.1074/jbc.M111.280446

G. Kozlov, A.Y. Denisov, M. Girard, M.-J. Dicaire, J. Hamlin, P.S. McPherson, B. Brais, and K. Gehring, "Structural Basis of Defects in the Sacsin HEPN Domain Responsible for Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS)," Journal of Biological Chemistry 286 (2011) 20407–20412. http://dx.doi.org/10.1074/jbc.M111.232884

R.O. Moyer, D.F.R. Gilson, B.H. Toby, "Neutron Powder Diffraction, and Solid-State Deuterium NMR Analyses of Yb2RuD6 and Spectroscopic Vibrational Analysis of Yb2RuD6 and Yb2RuH6," Journal of Solid State Chemistry 184 (2011) 1895-1898. http://dx.doi.org/10.1016/j.jssc.2011.04.012

B. Fortier-McGill, V. Toader, and L. Reven, "Chain Dynamics of Water-Saturated Hydrogen-Bonded Polymer Complexes and Multilayers," Macromolecules 44 (2011) 2755-2765. http://dx.doi.org/10.1021/ma102907w

R. Yang, S.A. Gaidamakov, J.W. Xie, J. Lee, L. Martino, G. Kozlov, A.K. Crawford, A.N. Russo, M.R. Conte, K. Gehring, R.J. Maraia, "La-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA Stability," Molecular and Cellular Biology 31 (2011) 542-556. http://dx.doi.org/10.1128/MCB.01162-10

L.A. Freiburger, O.M. Baettig, T. Sprules, A.M. Berghuis, K. Auclair, A.K. Mittermaier, "Competing allosteric mechanisms modulate substrate binding in a dimeric enzyme," Nature Structural & Molecular Biology 18 (2011) 288-294. http://dx.doi.org/10.1038/nsmb.1978

P.J. Farber, A. Mittermaier, "Concerted dynamics link allosteric sites in the PBX homeodomain," Journal of Molecular Biology 405 (2011) 819-830. http://dx.doi.org/10.1016/j.jmb.2010.11.016

2010

Q. Liu and K. Gehring, "Heterodimerization of BAK and MCL-1 Activated by Detergent Micelles," Journal of Biological Chemistry 285 (2010) 41202-41210. http://dx.doi.org/10.1074/jbc.M110.144857

A. Matte, G. Kozlov, J.F. Trempe, M.A. Currie, D. Burk, Z. Jia, K. Gehring, I. Ekiel, A.M. Berghuis, M. Cygler, "Preparation and characterization of bacterial protein complexes for structural analysis," Advances in protein chemistry and structural biology 76 (2009) 1-42. (review) http://dx.doi.org/10.1016/S1876-1623(08)76001-2

C. Riedinger, J. Boehringer, J.-F. Trempe, E.D. Lowe, N.R. Brown,
K. Gehring, M.E.M. Noble, C. Gordon, and J.A. Endicott, "Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12," Journal of Biological Chemistry 285 (2010) 33992–34003. http://dx.doi.org/10.1074/jbc.M110.134510

G. Kozlov, S. Bastos-Aristizabal, P. Määttänen, A. Rosenauer, F. Zheng, A. Killikelly, J.-F. Trempe, D.Y. Thomas and K. Gehring, "Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain," Journal of Biological Chemistry 285 (2010) 35551-35557. (JBC's Paper of the Week) http://dx.doi.org/10.1074/jbc.M110.160101

E. Matta-Camacho, G. Kozlov, F.F. Li and K. Gehring, "Structural basis of substrate recognition and specificity in the N-end rule pathway," Nature Structural & Molecular Biology 17 (2010) 1182–1187. http://dx.doi.org/10.1038/nsmb.1894

Q. Liu, T. Moldoveanu, T. Sprules, E. Matta-Camacho, N. Mansur-Azzam, K. Gehring, "Apoptotic Regulation by MCL-1 through Heterodimerization," Journal of Biological Chemistry 285 (2010) 19615-19624. http://dx.doi.org/10.1074/jbc.M110.105452

A.Y. Denisov, E. Kloser, D.G. Gray, A.K. Mittermaier, "Protein alignment using cellulose nanocrystals: practical considerations and range of application", J Biomol NMR 47 (2010) 195–204. http://dx.doi.org/10.1007/s10858-010-9423-y

S. Barelier, J. Pons, K. Gehring, J.-M. Lancelin and I. Krimm, "Ligand Specificity in Fragment-Based Drug Design," J. Med. Chem.53 (2010) 5256-5266. http://dx.doi.org/10.1021/jm100496j

P. Farber, H. Darmawan, T. Sprules and A. Mittermaier, "Analyzing Protein Folding Cooperativity by Differential Scanning Calorimetry and NMR Spectroscopy," Journal of the American Chemical Society 132 (2010) 6214-6222. http://dx.doi.org/10.1021/ja100815a

W. Tong, M. Gagnon, T. Sprules, M. Gilbert, S. Chowdhury, K. Meerovitch, K. Hansford, E.O. Purisima, J.W. Blankenship, N.-K.V. Cheung, K. Gehring, W.D. Lubell, H.U. Saragovi, "Small-Molecule Ligands of GD2 Ganglioside, Designed from NMR Studies, Exhibit Induced-Fit Binding and Bioactivity," Chemistry & Biology 17 (2010) 183-194. http://dx.doi.org/10.1016/j.chembiol.2010.01.012

G. Kozlov, M. Ménade, A. Rosenauer, L. Nguyen, K. Gehring, "Molecular determinants of PAM2 recognition by the MLLE domain of poly(A)-binding protein," Journal of Molecular Biology 397 (2010) 397-407. http://dx.doi.org/10.1016/j.jmb.2010.01.032

2009

J.-F. Trempe, C.X.-Q. Chen, K. Grenier, E.M. Camacho, G. Kozlov, P.S. McPherson, K. Gehring, and E.A. Fon, "SH3 Domains from a Subset of BAR Proteins Define a Ubl-Binding Domain and Implicate Parkin in Synaptic Ubiquitination," Molecular Cell 36 (2009) 1034-1047. http://dx.doi.org/10.1016/j.molcel.2009.11.021

A.K. Mittermaier, L.E. Kay, "Observing biological dynamics at atomic resolution using NMR," Trends in Biochemical Sciences 34 (2009) 601-611. (review) http://dx.doi.org/10.1016/j.tibs.2009.07.004

G. Kozlov, P. Maattanen, J.D. Schrag, G.L. Hura, L. Gabrielli, M. Cygler, D.Y. Thomas, K. Gehring, "Structure of the Noncatalytic Domains and Global Fold of the Protein Disulfide Isomerase ERp72," Structure 17 (2009) 651-659. http://dx.doi.org/10.1016/j.str.2009.02.016

E. Matta-Camacho, G. Kozlov, J.F. Trempe, K. Gehring, "Atypical Binding of the Swa2p UBA Domain to Ubiquitin," Journal of Molecular Biology 386 (2009) 569-577. http://dx.doi.org/10.1016/j.jmb.2008.09.086

A.Y. Denisov, P. Maattanen, C. Dabrowski, G. Kozlov, D.Y. Thomas, K. Gehring, "Solution structure of the bb' domains of human protein disulfide isomerase," Febs Journal 276 (2009) 1440-1449. http://dx.doi.org/10.1111/j.1742-4658.2009.06884.x

J.-P. Demers and A. Mittermaier, "Binding Mechanism of an SH3 Domain Studied by NMR and ITC," Journal of the American Chemical Society 131 (2009) 4355–4367. http://dx.doi.org/10.1021/ja808255d

B. Fortier-McGill and L. Reven, "2H NMR Studies of Polymer Multilayer Capsules, Films, and Complexes," Macromolecules 42 (2009) 247-254. http://dx.doi.org/10.1021/ma801929g

2008

T. Moldoveanu, K. Gehring, D.R. Green, "Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains," Nature 456 (2008) 404-408. http://dx.doi.org/10.1038/nature07353

M. Prakesch, A.Y. Denisov, M. Naim, K. Gehring, P. Arya, "The discovery of small molecule chemical probes of Bcl-X-L and Mcl-1", Bioorganic & Medicinal Chemistry 16 (2008) 7443-7449. http://dx.doi.org/10.1016/j.bmc.2008.06.023

R.O. Moyer, S.M. Antao, B.H. Toby, F.G. Morin, D.R. Gilson, "Neutron powder diffraction and solid-state 2H NMR studies of Ca2RuD6 and the stability of transition metal hexahydride salts", Journal of Alloys and Compounds 460 (2008) 138-141. http://dx.doi.org/10.1016/j.jallcom.2007.05.078

J.F. Trempe, E. Pomerantseva, K. Gehring, "REDOR recoupling in polymer-stabilized liquid crystals undergoing MAS - Two-dimensional NMR applications with strongly aligned proteins", Canadian Journal of Chemistry86 (2008) 608-615. http://dx.doi.org/10.1139/V08-048

J. Milette, C.T. Yim, L. Reven, "DNMR study of hydrophilic and hydrophobic silica dispersions in EBBA liquid crystals," Journal of Physical Chemistry B 112 (2008) 3322-3327. http://dx.doi.org/10.1021/jp077682y

A. Dorris, S. Rucareanu, L. Reven, C.J. Barrett, and R.B. Lennox, "Preparation and Characterization of Polyelectrolyte-Coated Gold Nanoparticles," Langmuir 24 (2008) 2532-2538. http://dx.doi.org/10.1021/la703003m

A. O'Donnell, K. Yach, and L. Reven, "Particle-Particle Interactions and Chain Dynamics of Fluorocarbon and Hydrocarbon Functionalized ZrO2 Nanoparticles," Langmuir 24 (2008) 2465-2471. http://dx.doi.org/10.1021/la702503m

H. Thérien-Aubin, X.X. Zhu, F. Ravenelle, and R.H. Marchessault, "Membrane Formation and Drug Loading Effects in High Amylose Starch Tablets Studied by NMR Imaging," Biomacromolecules 9 (2008) 1248-1254. http://dx.doi.org/10.1021/bm701256z

2007

P. Fiurasek, L. Reven, "Phosphonic and sulfonic acid-functionalized gold nanoparticles: A solid-state NMR study," Langmuir 23 (2007) 23 2857-2866. http://dx.doi.org/10.1021/la0629781

H. Thérien-Aubin, F. Janvier, W.E. Baille, X.X. Zhu and R.H. Marchessault, "Study of Hydration of Cross-Linked High Amylose Starch by Solid State 13C NMR Spectroscopy," Carbohydrate Research 342 (2007) 1525-1529. http://dx.doi.org/10.1016/j.carres.2007.04.014

2006

S. Pawsey, L. Reven, "19F Fast Magic-Angle Spinning NMR Studies of Perfluoroalkanoic Acid Self-Assembled Monolayers," Langmuir 22 (2006) 1055. http://dx.doi.org/10.1021/la051725p

D.F.R. Gilson, F.G. Morin, R.O. Moyer, "Deuterium NMR and Differential Scanning Calorimetric Studies of the Calcium Salts of Rhodium and Iridium Pentadeuterides, Ca2RhD5 and Ca2IrD5," Journal of Physical Chemistry B 110 (2006) 16487-16490. http://dx.doi.org/10.1021/jp062463i

J.R.L. Priqueler, I.S. Butler, F.D. Rochon, "An overview of 195Pt nuclear magnetic resonance spectroscopy" Applied Spectroscopy Reviews 41 (2006) 185-226. http://dx.doi.org/10.1080/05704920600620311