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Colin
Fyfe (Chemistry)
Suzana
Straus (Chemistry)
Elliott
Burnell (Chemistry)
Carl
Michal (Physics and Astronomy)
Ronald
Dong (Physics and Astronomy)
Lawrence
McIntosh (Biochemistry)
NMR
Facility (Department
of Chemistry)
G. Bouvignies, P. Vallurupalli, D.F. Hansen, B.E. Correia, O. Lange, A. Bah, R.M. Vernon, F.W. Dahlquist, D. Baker & L.E. Kay, "Solution structure of a minor and transiently formed state of a T4 lysozyme mutant," Nature 477 (2011) 111–114. http://dx.doi.org/10.1038/nature10349
T.
Wu, H. Mayaffre, S. Krämer, M. Horvatic, C. Berthier, W.N. Hardy,
R. Liang, D.A. Bonn and M.-H. Julien, "Magnetic-field-induced
charge-stripe order in the high-temperature superconductor YBa2Cu3Oy,"
Nature 477 (2011) 191–194. http://dx.doi.org/10.1038/nature10345
Dear Colleagues,
I am pleased to announce that the 5th VIVA (VIctoria VAncouver) NMR Symposium is to take place at St. John's College, UBC, Friday, July 29th, 2011.
The scope of this one day symposium is to bring together NMR users, researchers and managers from western Canada and the north-west of the USA to share information on topics of general NMR interest and to foster the development of an NMR community. Talks or poster presentations by graduate students working in any aspects of NMR are especially encouraged. Deadline for registration is July 15th, 2011.
Further details and registration info are available at http://www.chem.ubc.ca/viva/index.html
We look forward to seeing you all again.
Sincerely
Zhicheng (Paul) Xia
Department of Chemistry
University of British Columbia
2036 Main Mall
British Columbia V6T 1Z1
Tel: (604) 827 3548
Bruker Corporation (NASDAQ: BRKR) announces a major order from the University of British Columbia for its ultra-high field AVANCE™ III 850 spectrometer. The 850 MHz Nuclear Magnetic Resonance (NMR) magnet and spectrometer will enable researchers at the University of British Columbia and nearby Simon Fraser University to study the mechanisms of microbial diseases. Funds to purchase Canada's first 850 MHz actively-shielded compact NMR magnet were provided to the ASTRID (Advanced Structural Biology of Re-emerging Infectious Diseases) project by the Canada Foundation for Innovation, the British Columbia Knowledge Development Fund, and the University of British Columbia (UBC).
Bruker's new 850 MHz Ascend™ magnetThe AVANCE III 850 spectrometer is based on Bruker's new 850 MHz Ascend™ magnet that combines the key advantages of Bruker's well-established UltraShield™ Plus magnets with the superior performance and greater convenience delivered by advanced superconductor technology. This further innovation has enabled the design of smaller magnet coils, resulting in a significant reduction in the size of the cryostat. The new Ascend magnets are therefore easier to site, even safer to run and offer reduced operating costs. With over 160 ultra-high field installations worldwide, Bruker has an unmatched track record in NMR magnet technology.
The AVANCE III 850 system includes Bruker's high-sensitivity CryoProbe™ technology, enabling researchers to perform measurements on very small quantities of sample. In addition it is equipped with Bruker's latest Efree™ probe technologies offering state-of-the-art research tools for the investigation of membrane proteins in biological solid-state NMR.
Suzana K. Straus, Associate Professor of Chemistry at UBC, commented: "In recent years developments in the field of solid state NMR have led to an emergence of biomolecular methods to investigate membrane proteins. With this new magnet and probe technology, we are now able to determine the full three-dimensional structures and to characterize the membrane interactions of a range of peptides and proteins of interest. This will have great impact on our knowledge of infectious diseases."
"The incredible sensitivity and dispersion of the CryoProbe equipped solution and solid-state 850 MHz spectrometer will enable ASTRID researchers to carry out challenging structural and dynamic studies of the complex biomolecular machines used by notorious pathogens, including methicillin resistant Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis," said Lawrence McIntosh, Professor of Biochemistry & Molecular Biology and Chemistry at the University of British Columbia.
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DAXX
protein, also known as a "death-associated factor",
is an important player in many cell cycle processes. However the
detailed molecular structure of this important protein has not
been reported. In this cover article in Structure Lawrence
McIntosh (UBC) and his team has discovered using NMR spectroscopy
that the C-terminal half of DAXX is intrinsically disordered,
whereas the N-terminal portion contains a well-folded helical
bundle domain. This important work |
E. Escobar-Cabrera, D.K.W. Lau, S. Giovinazzi, A.M. Ishov, L.P. McIntosh, "Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C," Structure 18 (2010) 1642–1653. (Cover Article) http://dx.doi.org/10.1016/j.str.2010.09.016
University of British Columbia (June 29/10)
The Michael Smith Laboratories (MSL) and the Centre for High-throughput Biology (CHiBi) at the University of British Columbia are jointly launching a major recruiting initiative and invite applications for six new faculty positions. These full-time tenure-track positions will be filled primarily at the Assistant Professor level but exceptional candidates at a higher rank may be considered. The six new faculty will be located in exceptional research space at the centre of campus within a highly interdisciplinary and collaborative environment that includes biological and physical scientists and engineers, as well as proteomics and bioinformatics experts. The closing date for all applications is September 14, 2010.
For more information see the PDF poster (76 kB).
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P.T.
Eles, C.A. Michal,
"Two-photon excitation in nuclear magnetic and quadrupole
resonance," Progress in Nuclear Magnetic Resonance Spectroscopy
56 (2010) 232-246. (Invited Review) http://dx.doi.org/10.1016/j.pnmrs.2009.12.002
|
 |
Nuclear
Magnetic Resonance Spectroscopy of Liquid Crystals |
World Scientific: "This edited volume provides an extensive overview of how nuclear magnetic resonance can be an indispensable tool to investigate molecular ordering, phase structure, and dynamics in complex anisotropic phases formed by liquid crystalline materials. The chapters, written by prominent scientists in their field of expertise, provide a state-of-the-art scene of developments in liquid crystal research. The fantastic assortment of shape anisotropy in organic molecules leads to the discoveries of interesting new soft materials made at a rapid rate which not only inject impetus to address the fundamental physical and chemical phenomena, but also the potential applications in memory, sensor and display devices. The review volume also covers topics ranging from solute studies of molecules in nematics and biologically ordered fluids to theoretical approaches in treating elastic and viscous properties of liquid crystals. This volume is aimed at graduate students, novices and experts alike, and provides an excellent reference material for readers interested in the liquid crystal research. It is, indeed, a reference book for every science library to have."