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Burnell, Elliott (Chemistry)

Dong, Ronald (Physics and Astronomy)

Fyfe, Colin (Chemistry)

MacFarlane, Andrew (Chemistry)

McIntosh, Lawrence (Biochemistry)

Michal, Carl (Physics and Astronomy)

Straus, Suzana (Chemistry)

Xia, Zhicheng (Paul) (NMR Facility)

NMR Facility (Department of Chemistry)

Molecular Biophysics NMR Hub

11th VIVA NMR symposium, St. John's College, The University of British Columbia, July 21st, 2017 (May 20/17)

I am very pleased to announce the 11th VIVA NMR symposium is to be held at St. John's College, The University of British Columbia on July 21st, 2017.

VIVA NMR symposium is an annual NMR mini-symposium that is intended to foster a community among Pacific Northwest researchers using Nuclear Magnetic Resonance (NMR) spectroscopy. The idea is to provide a venue for student researchers to have the opportunity to give oral and poster presentations in a small welcoming environment, locally so it is affordable. We welcome presentations that are related to any sub-areas of NMR including, but not limited to, theoretical, method development or simply applications in your current research projects.

Registrations and details can be found on the following website:


Detailed programs will be furnished after the expiry date of the registration.

I look forward to welcoming you to VIVA NMR symposium.

Zhicheng Xia, Ph.D.
Director of The NMR Facilities
Department of Chemistry
University of British Columbia

Magnetic Resonance in Chemistry Special Issue: NMR of Liquid Crystals (Oct 9/14)

Magnetic Resonance in Chemistry Special Issue: NMR of Liquid Crystals

Magnetic Resonance in Chemistry

Special Issue: NMR of Liquid Crystals

October 2014, Volume 52, Issue 10 Pages 531–663

guest-edited by Ronald Y. Dong (UBC)

Ronald Y. Dong, "MRC special issue on NMR of liquid crystals," (Editorial) Magnetic Resonance in Chemistry 52 (2014) 531. http://dx.doi.org/10.1002/mrc.4109

Canadian contributions

A.P. Manning, M. Giese, A.S. Terpstra, M.J. MacLachlan, W.Y. Hamad, R.Y. Dong and C.A. Michal, "NMR of guest-host systems: 8CB in chiral nematic porous glasses" Magnetic Resonance in Chemistry 52 (2014) 532–539. http://dx.doi.org/10.1002/mrc.4101

A. Ferraz, J. Zhang, P.J. Sebastião, A.C. Ribeiro and R.Y. Dong, "Proton and deuterium nuclear spin relaxation study of the SmA and SmC* phases of BP8Cl-d17: a self-consistent analysis" Magnetic Resonance in Chemistry 52 (2014) 546–555. http://dx.doi.org/10.1002/mrc.4107

A.C.J. Weber, D.H.J. Chen, "Conformational problem of alkanes in liquid crystals by NMR spectroscopy" Magnetic Resonance in Chemistry 52 (2014) 560–569. (Review) http://dx.doi.org/10.1002/mrc.4124

E.E. Burnell, R.Y. Dong, A.C.J. Weber and A. Yethiraj, "NMR of solutes in nematic and smectic A liquid crystals: the anisotropic intermolecular potential," Magnetic Resonance in Chemistry 52 (2014) 570–580. (Review) http://dx.doi.org/10.1002/mrc.4113

J.L. Figueirinhas, R.Y. Dong, "NMR of bent-core nematogens: a mini-review," Magnetic Resonance in Chemistry 52 (2014) 614–624. (Review) http://dx.doi.org/10.1002/mrc.4097

NSERC 2014 Competition Results (June 27/14) [NSERC  ]

Discovery Grants

Blaine Chronik (Western) Magnetic Resonance Systems Development

Kalle Gehring (McGill) Protein folding in the endoplasmic reticulum

Paul Hazendonk (Lethbridge) Solid-State NMR of Complex Hybrid Organic-Inorganic Materials

Vladimir Ladizhansky (Guelph) Interactions of membrane proteins with lipids, water, and other proteins in biological membranes

Andrew MacFarlane (UBC) Development and Application of Depth-Resolved beta-Detected Nuclear Magnetic Resonance to electronic, ionic and molecular phenomena in the Solid State

Giuseppe Melacini (McMaster) Solution NMR Studies of Interactions of Ligands With Plasma Proteins

Anthony Mittermaier (McGill) Binding Mechanisms and Conformational Equilibria in Biomacromolecular Interactions

Geoffrey Ozin (Toronto) Silicon Nanochemistry

Linda Reven (McGill) Solid-State NMR of Polymer and Liquid Crystalline Nanocomposites

Andre Simpson (Toronto Scarborough) Development of flow-based and magic angle spinning in-vivo NMR to understand environmental stress

Jenifer Thewalt (Simon Fraser) Domains in Biologically Relevant Lipid Membranes

David Wishart (Alberta) Development of Improved Methods to Rapidly Characterize Protein Structure, Function and Dynamics

Julian Zhu (Université de Montréal) Versatile Polymeric Biomaterials

Discovery Accelerator Supplement
$120,000 over three years

Giuseppe Melacini (McMaster) Solution NMR Studies of Interactions of Ligands With Plasma Proteins

Research Tools and Instruments (RTI)

Derek Gates (UBC) Upgrade to UBC-Chemistry Departmental NMR Facility

8th Annual VIVA NMR Symposium (May 29/14)

Dear NMR Enthusiasts and Colleagues,

I am pleased to announce that the 8th VIVA (VIctoria VAncouver) NMR symposium is to take place at St. Johns College, UBC, Friday, August 8th, 2014.

The scope of this one day symposium is to bring together NMR users, researchers and managers from western Canada and the north-west of the USA to share information on topics of general NMR interest and to foster the development of NMR community. Talks or poster presentations by graduate students working in any aspects of NMR are especially encouraged. Deadline for registration is July 25th.

Further details and registration info are available at http://groups.chem.ubc.ca/viva

I am looking forward to welcoming you at VIVA.



Zhicheng (Paul) Xia, Ph.D.
NMR Facilities
Department of Chemistry
University of British Columbia
2036 Main Mall, Vancouver BC V6T1Z1

CSC 2014 Call for Papers is now open (Dec 16/13)

Canadian eventCSC 2014 “Chemistry from Sea to Sky" the 97th Canadian Chemistry Conference and Exhibition, June 1-5, 2014, Vancouver, B.C., Canada


Solid-state NMR Symposium

Suzana Straus, University of British Columbia
Rob Schurko, University of Windsor

Confirmed Invited Speakers:
David Bryce, University of Ottawa
Brad Chmelka, University of California - Santa Barbara, USA
Yoshitaka Ishii, University of Illinois - Chicago, USA
Scott Kroeker, University of Manitoba
Vlad Ladizhansky, University of Guelph
Rachel Martin, University of California - Irvine, USA
Len Mueller, University of California - Riverside, USA

Encyclopedia of Magnetic Resonance: new entries (Oct 25/13)NMR in crystallography

(2013) volume 2, issue 3

A.J. Simpson, D. Courtier-Murias, J.G. Longstaffe, H. Masoom, R. Soong, L. Lam, A. Sutrisno, H. Farooq, M.J. Simpson, W.E. Maas, M. Fey, B. Andrew, J. Struppe, H. Hutchins, S. Krishnamurthy, R. Kumar, M. Monette, H.J. Stronks, "Environmental Comprehensive Multiphase NMR," eMagRes 2 (2013) 399–414. http://dx.doi.org/10.1002/9780470034590.emrstm1337

W.L. Meerts, C.A. de Lange, A.C.J. Weber, E.E. Burnell, "Analysis of Complex High-Resolution NMR Spectra by Sophisticated Evolutionary Strategies," eMagRes 2 (2013) 437–450. http://dx.doi.org/10.1002/9780470034590.emrstm1309

Recognition: 54th ENC Student Travel Awards (May 1/13)

Following the long tradition, ENC has awarded 2013 Student Travel Stipends to support students attending the 54th ENC Conference held April 14-19, 2013 in Asilomar, California. The stipends were provided by the ENC, the Suraj P. Manrao Science Foundation, and by the generous contributions of sponsors. Among awardees there were several Canadian recipients, including

Jasmine Viger-Gravel (University of Ottawa)
Daryl Good (University of Guelph)
Leayen Lam (University of Toronto)
Alan Manning (University of British Columbia)
Danielle Smiley (McMaster University)
Stanislav Veinberg (University of Windsor)

Congratulations to all the winners!

The final 54th ENC program is now available online

NMR Technician position, UBC Chemistry (Sept 11/12)

University of British Columbia, Department of Chemistry is seeking an NMR Technician (Job ID: 13930, Research Assistant/Tech 4). This position is a temporary maternity leave replacement for 12 months and can start as soon as possible (NMR Facility).

Responsibilities include: assisting the departmental NMR facility manager to maintain five Bruker solution and one solid state NMR spectrometers; offer training and instruction to NMR users; help users to implement and develop NMR methods; and to run service samples for the NMR clients.

Requirements: Masters Degree in Chemistry or Physics with a minimum of two years of NMR experience.

For more information and to apply online visit
http://www.hr.ubc.ca/careers-postings/staff.php (Job ID: 13930)
or send resume with two reference letters to Paul Xia [zcxia "at" chem.ubc.ca] before September 21, 2012.

"Canadian NMR Research" News Bulletin (Feb 10/12)

Winter 2012

The Winter 2012 Issue of the "Canadian NMR Research" news bulletin is now available for download.

You are welcome to share it with your colleagues and students.

Thanks for reading!

Two NMR papers in Nature (Sept 12/11)

G. Bouvignies, P. Vallurupalli, D.F. Hansen, B.E. Correia, O. Lange, A. Bah, R.M. Vernon, F.W. Dahlquist, D. Baker & L.E. Kay, "Solution structure of a minor and transiently formed state of a T4 lysozyme mutant," Nature 477 (2011) 111–114. http://dx.doi.org/10.1038/nature10349

T. Wu, H. Mayaffre, S. Krämer, M. Horvatic, C. Berthier, W.N. Hardy, R. Liang, D.A. Bonn and M.-H. Julien, "Magnetic-field-induced charge-stripe order in the high-temperature superconductor YBa2Cu3Oy," Nature 477 (2011) 191–194. http://dx.doi.org/10.1038/nature10345

5th VIVA NMR symposium (April 22/11)

Dear Colleagues,

I am pleased to announce that the 5th VIVA (VIctoria VAncouver) NMR Symposium is to take place at St. John's College, UBC, Friday, July 29th, 2011.

The scope of this one day symposium is to bring together NMR users, researchers and managers from western Canada and the north-west of the USA to share information on topics of general NMR interest and to foster the development of an NMR community. Talks or poster presentations by graduate students working in any aspects of NMR are especially encouraged. Deadline for registration is July 15th, 2011.

Further details and registration info are available at http://www.chem.ubc.ca/viva/index.html

We look forward to seeing you all again.


Zhicheng (Paul) Xia
Department of Chemistry
University of British Columbia
2036 Main Mall
British Columbia V6T 1Z1

Tel: (604) 827 3548

850 MHz NMR System at UBC (Dec 15/10)

University of British Columbia Orders Canada's First Compact 850 MHz NMR System from Bruker to Enable Research on Microbial Diseases

Vancouver, British Columbia, December 15, 2010 (press release)

Bruker Corporation (NASDAQ: BRKR) announces a major order from the University of British Columbia for its ultra-high field AVANCE™ III 850 spectrometer. The 850 MHz Nuclear Magnetic Resonance (NMR) magnet and spectrometer will enable researchers at the University of British Columbia and nearby Simon Fraser University to study the mechanisms of microbial diseases. Funds to purchase Canada's first 850 MHz actively-shielded compact NMR magnet were provided to the ASTRID (Advanced Structural Biology of Re-emerging Infectious Diseases) project by the Canada Foundation for Innovation, the British Columbia Knowledge Development Fund, and the University of British Columbia (UBC).

Bruker's new 850 MHz Ascend™ magnetThe AVANCE III 850 spectrometer is based on Bruker's new 850 MHz Ascend™ magnet that combines the key advantages of Bruker's well-established UltraShield™ Plus magnets with the superior performance and greater convenience delivered by advanced superconductor technology. This further innovation has enabled the design of smaller magnet coils, resulting in a significant reduction in the size of the cryostat. The new Ascend magnets are therefore easier to site, even safer to run and offer reduced operating costs. With over 160 ultra-high field installations worldwide, Bruker has an unmatched track record in NMR magnet technology.

The AVANCE III 850 system includes Bruker's high-sensitivity CryoProbe™ technology, enabling researchers to perform measurements on very small quantities of sample. In addition it is equipped with Bruker's latest Efree™ probe technologies offering state-of-the-art research tools for the investigation of membrane proteins in biological solid-state NMR.

Suzana K. Straus, Associate Professor of Chemistry at UBC, commented: "In recent years developments in the field of solid state NMR have led to an emergence of biomolecular methods to investigate membrane proteins. With this new magnet and probe technology, we are now able to determine the full three-dimensional structures and to characterize the membrane interactions of a range of peptides and proteins of interest. This will have great impact on our knowledge of infectious diseases."

"The incredible sensitivity and dispersion of the CryoProbe equipped solution and solid-state 850 MHz spectrometer will enable ASTRID researchers to carry out challenging structural and dynamic studies of the complex biomolecular machines used by notorious pathogens, including methicillin resistant Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis," said Lawrence McIntosh, Professor of Biochemistry & Molecular Biology and Chemistry at the University of British Columbia.

Cover article in Structure (Dec 8/10)


DAXX protein, also known as a "death-associated factor", is an important player in many cell cycle processes. However the detailed molecular structure of this important protein has not been reported. In this cover article in Structure Lawrence McIntosh (UBC) and his team has discovered using NMR spectroscopy that the C-terminal half of DAXX is intrinsically disordered, whereas the N-terminal portion contains a well-folded helical bundle domain. This important work
provides a structural foundation for understanding the diverse functions of DAXX.

E. Escobar-Cabrera, D.K.W. Lau, S. Giovinazzi, A.M. Ishov, L.P. McIntosh, "Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C," Structure 18 (2010) 1642–1653. (Cover Article) http://dx.doi.org/10.1016/j.str.2010.09.016

Thesis Defenses (July 29/10)

Adrian Weber
(Chemistry, UBC) July 2010
Supervisor: Elliott Burnell
External examiner: Rod Wasylishen attended
PhD thesis "Chemical Physics and the Condensed Phase: NMR Studies in a Liquid-Crystal Testing Ground"

Canadian job University of British Columbia (June 29/10)

The Michael Smith Laboratories (MSL) and the Centre for High-throughput Biology (CHiBi) at the University of British Columbia are jointly launching a major recruiting initiative and invite applications for six new faculty positions. These full-time tenure-track positions will be filled primarily at the Assistant Professor level but exceptional candidates at a higher rank may be considered. The six new faculty will be located in exceptional research space at the centre of campus within a highly interdisciplinary and collaborative environment that includes biological and physical scientists and engineers, as well as proteomics and bioinformatics experts. The closing date for all applications is September 14, 2010.

For more information see the PDF poster (76 kB).

Review in Progress in NMR Spectroscopy (March 10/10)

P.T. Eles, C.A. Michal, "Two-photon excitation in nuclear magnetic and quadrupole resonance," Progress in Nuclear Magnetic Resonance Spectroscopy 56 (2010) 232-246. (Invited Review) http://dx.doi.org/10.1016/j.pnmrs.2009.12.002

NMR Books (Oct 28/09)

NMR in Liquid Crystals

Nuclear Magnetic Resonance Spectroscopy of Liquid Crystals

edited by Ronald Dong (University of British Columbia)
Hardcover: 464 pages
Publisher: World Scientific; September 2009
Language: English
ISBN: 978-981-4273-66-4

World Scientific: "This edited volume provides an extensive overview of how nuclear magnetic resonance can be an indispensable tool to investigate molecular ordering, phase structure, and dynamics in complex anisotropic phases formed by liquid crystalline materials. The chapters, written by prominent scientists in their field of expertise, provide a state-of-the-art scene of developments in liquid crystal research. The fantastic assortment of shape anisotropy in organic molecules leads to the discoveries of interesting new soft materials made at a rapid rate which not only inject impetus to address the fundamental physical and chemical phenomena, but also the potential applications in memory, sensor and display devices. The review volume also covers topics ranging from solute studies of molecules in nematics and biologically ordered fluids to theoretical approaches in treating elastic and viscous properties of liquid crystals. This volume is aimed at graduate students, novices and experts alike, and provides an excellent reference material for readers interested in the liquid crystal research. It is, indeed, a reference book for every science library to have."